Resume & Curriculum Vitae Philip K. Lane Contact Information email: lanephil<"at" sign> (must replace <"at" sign> with the character @) telephone: 510.843.1877 fax: 425.740.0973 cell: 415.710.5456 post [>9/1/05]: 2416 Hillside Avenue, Berkeley, CA. 94704-2528, USA web: Job Objective Challenging short-term or contract scientific research, remote field operations, science/engineering project management, systems analysis, troubleshooting, biotechnology, and/or out-of-country consulting opportunity. Timeframe: 1-6 months fulltime or parttime, depending on project requirements; repeat stints desirable. Overseas, extreme, and/or wilderness worksites especially desired. Summary Scientist, biologist, microbiologist, systems analyst, science / engineering project manager, physician, clinical pathologist, with diverse experience and skills sets, currently developing a private consulting practice focusing on short-term contract scientific research, science and engineering project management, remote field operations, systems analysis, biotechnology, and out-of- country projects, with particular emphasis on overseas, extreme, and/or wilderness worksites. Worked for 9 years in several capacities in the astrobiology program of NASA. Most recently worked on spaceflight operations as Science flight operations controller, Replan shift, JSC mission control, for Neurolab, a NASA Spacelab space shuttle mission dedicated to neurosciences research (STS-89, April 1998). Prior work as Deputy Payload Scientist on BION-11, a Russian-French-U.S. collaborative spaceflight set of primate experiments (Moscow, Russia, December 1996), and as Payload Scientist for NIHR3, a mammalian development (rodent dam and neonate) spaceflight experiment (STS-72, January 1996), a precurser experiment preparatory for Neurolab. Prior work as Payload Scientist on definition, development, integration, implementation, and project technical management of numerous life sciences spaceflight experiments in Small Payloads program of Space Shuttle system. Prior laboratory research experience with publications in molecular biology, virology, and clinical epidemiology. Extensive international experience including work stints in Gabon (Africa), France, Moscow, and London . Trained as a physician (M.D. degree, Harvard University) and microbiologist (coursework equivalent of B.S.). Board certified Pathologist (Laboratory Medicine / Clinical Pathology). Coursework background in engineering, mathematics, physics, computer science, and international relations (A.B. degree in International Relations, Stanford University). Currently undertaking small aircraft flight training and other activities in support of application to Astronaut Candidate Program, NASA. Biomedical Training, Licensure, and Board Certification 1989 - Board Certified Pathologist - American Board of Pathology (Clinical Pathology) 1987-1990 - Postdoctoral Fellow - Transfusion Medicine program, Department of Laboratory Medicine, University of California San Francisco 1986 - Physician and Surgeon's License - State of California (expiration 5/31/2002) 1986 - DEA Registration - U.S. Deptartment of Justice, Drug Enforcement Agency (DEA), Schedule III-IV-V level registration (expiration 3/31/2003) 1986-1988 - Residency - Laboratory Medicine, University of California San Francisco 1985-1986 - Internship - Laboratory Medicine, University of California San Francisco Education 2001-current - Russian language studies. Moscow State University (Moskovskiy Gosudarstvenny Universityet), Moscow, Russia, 12/2000 - 1/2001. Continued Russian language studies on independent basis in progress. 1998-current - Flight Training - Sierra Academy of Aeronautics, Oakland International Airport, Oakland, CA. Fixed-wing aircraft pilot training. Federal Aviation Administration (FAA) Private Pilot license, Airplane Single Engine Land (ASEL), issued 31 August 2000. Additional flight training in progress. 1995 - High Altitude Physiologic Training - Edwards Air Force Base, Edwards, CA. In support of National Aeronautics and Space Administration (NASA) KC-135 reduced-gravity aircraft program Neurolab experimentation. 1986-1990 - Engineering Coursework - San Francisco State University, San Francisco, CA. Statics, AUTOCAD, FORTRAN, materials science, electronic networks. 1989 - "Epidemiologic Design in Biomedical Research" - University of California, San Francisco, CA. 1987 - "Methods of Recombinant DNA Research" - New England Biolabs and Smith College, Dedham, MA. 1981-1985 - Doctorate in Medicine (M.D.) - Harvard Medical School, Boston, MA. Preclinical and clinical coursework including epidemiology, molecular virology, medical ethics, pathology, and 3- month tropical medicine clinical rotation at Schweitzer Hospital, Lambarene, Gabon, Africa. M.D. awarded June 1985. 1979-1980 - Premedical and Microbiology Coursework - Stanford University, Stanford, CA. Coursework equivalent of B.S. in Medical Microbiology. 1973-1978 - Bachelor of Arts (A.B.) - International Relations, Stanford University, Stanford, CA. Coursework in calculus, thermodynamics, physics, nuclear energy, economics, science journalism, political science, history, arms control, technology transfer, third world development, law of the sea. Self-designed major entitled "International Applications of Technology". Graduated "Phi Beta Kappa" and "with distinction" (top 25% of graduating class); A.B. awarded June 1978. Honor Society 1978 - Phi Beta Kappa Experience and Work History Senior Scientist / Payload Scientist Oct. 1990-Dec. 1999 (9 years 2 months) National Aeronautics and Space Administration - Lockheed Martin Engineering and Sciences, Western Programs Office, Flight Payloads Integration Program. Space Life Sciences Division, Science Operations Branch, NASA / Ames Research Center, Moffett Field, CA. Definition, design, development, verification, implementation, integration, documentation, scheduling, tracking, and operational management for life sciences experiments to be flown on the Space Shuttle (Space Transportation System, STS). Recent experience includes: (1) systems analyst for the Electronic Data Collection System, a database system developed to track rodent launch candidate group experimental data (> 20,000 database records), in prelaunch KSC (Kennedy Space Center, Florida) operations for Neurolab (STS-89, April 1998); (2) science flight operations controller, Johnson Space Center (JSC) Replan shift, during STS-89 on-orbit period (JSC mission control, Houston, TX., April 1998); (3) Deputy Payload Scientist for BION-11 flight operations (Moscow, Russia, December 1996), an unmanned primate experiments collaborative project with Russian, French, and U.S. participation using a Russian launch vehicle; (4) Payload Scientist for NIH.R3, a Space Shuttle middeck locker Small Payload experiment involving the first spaceflight of nursing rat dams and neonates, as a proof- of-concept experiment preparatory for Neurolab, on STS-72, Jan. 1996; (5) consultant for science support team (formerly team lead), Mammalian Development experiment group for Neurolab; (6) science support for the R-RAHF (Rodent Research Animal Housing Facility) Nursing Insert redesign program in support of Neurolab, including extensive hardware biocompatibility testing with nursing rat dams and neonates; (7) science support for the AEM-NF (Animal Enclosure Module - Nursing Facility) redesign program in support of NIH.R3, including biocompatibility testing with nursing rat dams and neonates; (8) science support for Advanced Animal Habitat (AAH) engineering development team; (9) science support for Standard Interface Glovebox (SIGB) engineering development team; and (10) Experience in planning and conduct of an AEM-NF rodent experiment on the NASA KC-135 Reduced Gravity Program aircraft, Ellington Airfield, Houston, TX., April 1995, in support of NIHR3. Extensive interactions with principal investigators, engineering staff, and payloads management staff. Assistance to principal investigator in all aspects of the conduct of the experiment, including design, documentation, preflight preparation, flight support operations, postflight analysis, and supporting ground studies. Preparation of requirements documents, procedures, design reviews, and other documentation to support experiments and hardware development. Interactions with design engineers to define hardware specifications and track hardware construction. Interactions with crew training staff to provide input for astronaut activities scheduling, and direct participation in astronaut training activities. Intensive involvement in operational support of flight experiments. Working environment includes frequent interactions with approximately 35 other support scientists (degrees including B.S., M.S., and Ph.D.) with similar responsibilities, with engineering staff, and with university-based Principal Investigators. Prior experience: Primary planning and operational responsibility (as Payload Scientist) for spaceflight life sciences Small Payloads program experiments: PSE.4/STS-62/March 1994 (Physiologic Systems Experiment - 4, a rodent spaceflight experiment); PSE.3/STS-57/June 1993; PHCF/STS-46/July 1992 (Pituitary Growth Hormone Cell Function experiment, a spaceflight tissue culture experiment). Assistance with additional spaceflight life sciences experiments: SLS-1/STS-40/June 1991 (Spacelab Life Sciences - 1); PARE.1/STS-48/Sept. 1991 (Physiologic and Anatomic Rodent Experiment - 1); IML-1/STS-42/Jan. 1992 (International Microgravity Laboratory - 1), PARE.2/STS-54/Jan. 1993, PARE.3/STS-56/Mar. 1993, IMMUNE.1/STS-60/January 1994 (Immunology Rodent Experiment - 1). Additional activities: (1) Support to other small (middeck) payloads and other life sciences payloads, including ground laboratory configuration, logistics, and planning. (2) Shared microbiologist responsibilities, including participation in management of SPF (specific pathogen free) testing protocol for small payloads. (3) Experiment definition activities for potential future life sciences experiment payloads. (4) Acting Science department manager, interim basis. (5) Acting Gravitational Biology Section Supervisor and Acting Science Support Section Supervisor, interim basis. (6) Science support for the SLS-1 Biospecimen Sharing Program, including cryogen supply operations for the dissection teams, chemical spill safety program, and biospecimen shipping operations at KSC and Dryden Flight Research Facility (DFRF, Edwards Air Force Base, Edwards, CA.). (7) Designed and conducted an analysis of funding, productivity, and achievements of NASA / ARC / Code SL-supported principal investigators. Assistant Research Physician 1990 (3 months) Postdoctoral Fellow 1987-1990 (2 years 10 months) University of California San Francisco - Department of Laboratory Medicine, Transfusion Research Program. San Francisco, CA. Laboratory and epidemiologic studies of molecular biology of post transfusion hepatitis (PTH), with particular focus on hepatitis B virus, non-A non-B hepatitis, and recently discovered hepatitis C virus (HCV). Additional work on human immunodeficiency virus (HIV). Designed epidemiologic study of PTH viral nucleic acid sequences in archived pathology specimens; helped design and develop reverse transcriptase - polymerase chain reaction (RT- PCR) method for testing for and cloning of HCV; extensive writing experience (human subjects committee protocols, recombinant DNA approval application, fellowship and program project project grant renewal applications, several scientific papers). Laboratory methods: reverse transcription, cloning, DNA sequencing, western and southern blots, polymerase chain reaction for detection of viral nucleic acid sequences in clinical specimens, large segment PCR for cloning, negative stain electron microscopy, case-control and other epidemiologic study design. Research Assistant 1982 (4 months) Harvard Medical School - Department of Physiology, Aerospace / Circadian Physiology Laboratory. Boston, MA. Assisted in design and implementation of a ground-based weightlessness simulation system employing electroencephalogram (E.E.G.) monitoring and lower body positive pressure (LBPP) in squirrel monkeys. Evaluated effect of LBPP on latency to sleep onset. Methods: primate surgery, permanent E.E.G. electrode placement, and wiring harness design; LBPP apparatus design and construction; computer-assisted E.E.G. data collection and analysis. Research Assistant 1979-1981 (1 year 10 months) Stanford University - Department of Medical Microbiology, Bacterial Genetics Laboratory. Stanford, CA. Research in genetics of repressor mutations in Salmonella typhimurium. DNA genetics methods including phage transduction; evaluation of effect of repressor mutations on mouse virulence. Constructed specific repressor-positive phage and bacterial strains; designed and performed mouse virulence studies. Other Experience Small Aircraft Flight Training (1998-current-) - Sierra Academy of Aeronautics, Oakland International Airport, Oakland, CA. FAA Private Pilot license (ASEL) issued 31 August 2000. Instrument rating training in progress. Approximately 131 flight hours to date. Marathon Run (1999-current) - February 1999 began road and trail running. Completed Skyline 50K Endurance Run (Hayward, CA.), August 2000, approximately 31 miles (5 miles longer than a marathon run), including 4,740 foot elevation gain. Climbed Mount Conness Peak (September 2000) - Sierra Nevada mountain range, California; ~12,590 feet elevation, personal best to date. Pollwatcher (March 2000) - California primary election, Alameda County Registrar of Voters, Berkeley precinct 209310. Formal title "Poll Inspector", responsible for setup and takedown of poll site, physical handling and counts of all ballots for precinct, oversight of activities of 3 additional pollwatch staff. Antarctic Cruise Expedition (February 1998) - on S.S. Bremen (Ushuia, Argentina; Falklands Islands, U.K., and Antarctic peninsula). Round-the-World Voyage (February 1997) - including trans- Siberian train trip Moscow to Vladivostok. First "Century" 100-mile Bikeride (March 1996) - Leavenworth, KS. Wildflower Century. Additional century bikerides each year since, including Grizzly Peak Century, Moraga, California, May 2000, 108 miles plus 8300 foot elevation gain. Microgravity Flight Experience (April 1995) - NASA KC-135 aircraft, Reduced Gravity program, Ellington Airfield, Houston, TX. Dolphin Communication Research (1990) - Earthwatch expedition, University of Hawaii at Honolulu. Assisted research in symbolic and syntactic language skills of captive dolphins. Transfusion Research Forum (1988-1990) - U.C.S.F. Co- organizer of transfusion medicine weekly seminar series. Trans-Sierra Ski Trip (1989) - Participate in 8 day snowcamp/ski trip from Mammoth to Yosemite. Additional snowcamping trips in Sierra Nevada (CA.) mountains most years since. Research Scuba Diving (1989) - Baja California. Assisted in coral reef ecology studies. University Research Expeditions, Univ. of Calif. Berkeley and Scripps Institute, U.C. San Diego. Intern (1984) - Albert Schweitzer Hospital, Lambarene, Gabon, Africa. Worked as physician in jungle hospital in Africa. Coordinator (1981-1982) - Washington Project. Nuclear War Study Group, Harvard Medical School. Organized student/faculty educational contacts with members of Congress on medical consequences of nuclear war. Foreign Service Officer Program (1989) - U.S. Department of State. Passed written and oral exams but elected not to pursue this career option. Teaching Associate (1979) - Institute for International Studies and Training, Shizuoka Province, Japan. Teaching English as a second language. Research Coordinator (1978) - Reference Research Associates, Palo Alto, CA. Arms control research. Congressional Student Intern (1976) - District Office, Congressman Paul McCloskey, Jr., Palo Alto, CA. University Committee Member (1976) - Committee on Foreign Study Programs, Stanford University. Year Abroad (1975) - Studied French at Stanford University overseas campus at Tours, France; worked on a farm in France; worked in a department store in London, traveled extensively in Europe. Professional Affiliations and Journals 1995 - "Lancet" 1995 - New York Academy of Sciences 1990 - American Society for Gravitational and Space Biology 1986 - Aerospace Medical Association 1986 - "Science" (American Association for the Advancement of Science) 1986 - "Nature" 1986 - "Scientific American" 1970 - "Science News" Additional Affiliations 1990 - Nature Conservancy 1990 - Natural Resources Defense Council (NRDC) 1990 - British Interplanetary Society 1990 - American Civil Liberties Association (ACLU) 1990 - Union of Concerned Scientists (UCS) 1985 - The Planetary Society 1980 - Amnesty International (AI) 1980 - Sierra Club Languages French - fluent spoken and written French. Russian - basic spoken and written Russian. Other languages - partial knowledge of: Japanese, German, Swahili, Spanish, Italian, Portuguese. Computer languages - database (Filemaker, DBASE), web design and HTML, word processing, telecommunications, drafting (Autocad), DNA sequence analysis, and spreadsheet microcomputer software; Ethernet LAN administration; DOS, MS Windows, Macintosh, UNIX operating systems; Fortran, Basic programming languages; medical literature database search programs; global internet communications, file transfer, email, world wide web, and data searches. Interests Experienced runner, bicyclist, backcountry and downhill skier, backpacker, scuba diver. Interests include xenobiology, spaceflight, solar system exploration, electrical engineering, physics, aerospace physiology, cosmology, meterology and atmospheric physics, vulcanology, infectious diseases, microbiology of extreme environments, global "third world" development, global population control, global economic sustainability and environmental preservation. Strengths Diverse experience and wide knowledge base. Superb capabilities in troubleshooting complex systems. Strengths include intelligence, stamina, dedication, passion, teamwork, leadership skills, and interpersonal skills, including work with foreigners and in foreign cultures and languages. Skills include project management; analysis and repair of complex systems, including skilled selection of proper queries, investigations, and experiments; systems analysis; superior troubleshooting skills; work under mission-critical deadlines; and realtime operations in rapidly changing circumstances. Skilled observer of living and other experimental systems; skills in experimental design, including in particular design of appropriate control groups; rapid acquisition of new skills; broad range of work and life experiences. Goals Travel to, work in low earth orbit & beyond. Travel to, work in Antarctica (partially complete). Learn fluent Russian (in progress); learn fluent Spanish. Round-the-world trip (complete). Trans-Siberian train trip (complete). Run marathon (complete). Bicycle 100-mile "century" ride (complete). Ironman Triathalon (training in progress). Alcatraz to San Francisco swim. Pilot license (complete; additional flight training in progress). Acquire zero-gravity environment artifacts (complete). Climb Mt. Shasta; climb Mt. Whitney; climb an 8000 meter peak. Trans Sierra ski trip (complete). Visit or work on an aircraft carrier. Sea kayak under Golden Gate Bridge, San Francisco (complete). Drive around Australia. Publications and Presented Papers Lane PK et al (manuscript in preparation): Observations of Altered Fluid Homeostasis and Significantly Reduced Water Intake Among Spaceflight-Exposed Rats (Rattus norvegicus) in US Space Shuttle Flight Experiments, 1990-1998. Borkowski GL, Wilfinger WW, Lane PK. Laboratory Animals in Space Life Sciences Research. Animal Welfare Information Center (AWIC) Newsletter (non-peer-reviewed), Vol. 6 # 2-4, pages 1-7, National Agricultural Library, Agricultural Research Service, United States Department of Agriculture (USDA), Beltsville, MD., U.S.A., Winter 1995/1996. Lane PK, Ostrach LH, Rodriguez S, Kwong J, Howerton T, Sing L, Bonzales B, Hinds WE, Mayer D, Maese AC, Mulenburg G. Modification of the Research Animal Holding Facility (RAHF) to Support Nursing Rats and Their Litters During Spaceflight (abstract, paper, and oral presentation). Society of Automotive Engineers (SAE), Inc. ("The Engineering Society for Advancing Mobility, Land Sea Air and Space, International"): 25th International Conference on Environmental Systems, 7/10-13/95, San Diego, CA. SAE Technical Paper Series, Paper # 951478 (1995; SAE, Warrendale, PA., USA). Hymer WC, Grindeland RE, Salada T, Nye P, Grossman EJ, Lane PK. Experimental Modification of Rat Pituitary Growth Hormone Cell Function During and After Spaceflight. J Appl Physiol 1996 March; 80(3):955-970. Hymer WC, Grindland R, Salada T, Grossman E, Nye P, Gosselink K, Avery L, Ball R, Lane PK. Rat pituitary Growth Hormone (GH) cells are Sensitive to Microgravity (uG): STS-46 results (abstract/talk). Presented at the Americal Society for Gravitational and Space Biology annual meeting, Washington D.C., Oct. 20-23, 1993. Lane PK, Jahns G, Berthold R. Preflight planning and flight operations for the Pituitary Growth Hormone Cell Function Experiment (PHCF), a Space Shuttle middeck locker experiment (abstract/poster). Presented at the Americal Society for Gravitational and Space Biology annual meeting, Washington D.C., Oct. 20-23, 1993. Ulrich PP, Romeo JR, Lane PK, Kelly I, Daniel LJ, Vyas GN. Detection, semi-quantitation, and genetic variation in hepatitis C virus sequences amplified from the plasma of blood donors with elevated alanine aminotransferase. J Clin Invest 1990 November; 86(5):1609-1614. Lane PK, Vyas GN. Hepatitis and Transfusion in the 1980's (review). San Francisco Medicine, July 1989. (non peer reviewed journal) Hwang L-Y, Beasley RP, Busch MP, Lane PK, Vyas GN. Human immunodeficiency virus seroprevalence among blood product recipients in San Francisco before transfusion. Transfusion 1989; 29:113-118. Stricker RB; Lane PK; Leffert JD; Rodgers GM; Shuman MA; Corash L. Development of antithrombin antibodies following surgery in patients with prosthetic cardiac valves. Blood 1988 October; 72(4):1375-1380. Lane PK; Embury SH; Toy PT. Oxygen-induced marrow red cell hypoplasia leading to transfusion in sickle painful crisis. Am J Hematol 1988 January; 27(1):67-68. Lane PK; Townsend RM; Beckstead JH; Corash L. Central nervous system involvement in a patient with chronic lymphocytic leukemia and non-Hodgkin's lymphoma (Richter's syndrome), with concordant cell surface immunoglobulin isotypic and immunophenotypic markers. Am J Clin Pathol 1988 February; 89(2):254-259. Philip K. Lane, M.D. Resume and Curriculum Vitae 12 January 2002

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