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State of the World 2023: Bruce Sterling and Jon Lebkowsky
permalink #51 of 338: The Year of the Rabid (jonl) Thu 5 Jan 23 07:02
permalink #51 of 338: The Year of the Rabid (jonl) Thu 5 Jan 23 07:02
A fair amount of apocalyptic thinking could creep into this year's conversation. The anthropocene might be the latest geological age to culminate in an extinction event, probably of our own making. Seeing this, some billionaires offered Doug Rushkoff money to help them devise a plan for surviving whatever might be coming. He didn't take their money, but his meeting inspired him to write a book, "Survival of the Richest." He talks about "the mindset" that is common among tech bro billionaires, "a belief that with enough money and technology, wealthy men can live as gods and transcend the calamities that befall everyone else. It's a way of applying the 'exit strategy' of a Silicon Valley startup to civilization itself." (Note that he said "wealthy men" - what are wealthy women thinking?) "The Mindset is rooted in empirical science: the reduction of nature and complexity, the domination of others, and the extraction of substance and energy from the real world and its conversion into symbol systems, like money. Digital technologies catalyzed and amplified The Mindset, yielding tech billionaires who believe that they can lord over us and then leave us behind as they migrate to humanity's next phase of existence." I think Doug realized that these billionaires are not geniuses, though they and others may assume so. They had some skills, no doubt, but luck was a factor in their ascendance. Also post-Reagan policy changes that helped the rich get richer. "Whether they're considering climate change, economic collapse, social unrest, energy policy, or food scarcity, I'm convinced they have no real idea what's going on or what to do about it. They have no more of a clue than the rest of us. Maybe less. And I'm not sure whether that should make us feel scared or emboldened." Doug Rushkoff, Survival of the Richest: Escape Fantasies of the Tech Billionaires (p. 181).
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State of the World 2023: Bruce Sterling and Jon Lebkowsky
permalink #52 of 338: Jon Lebkowsky (jonl) Thu 5 Jan 23 07:47
permalink #52 of 338: Jon Lebkowsky (jonl) Thu 5 Jan 23 07:47
<scribbled by jonl Thu 5 Jan 23 11:37>
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State of the World 2023: Bruce Sterling and Jon Lebkowsky
permalink #53 of 338: fruitbatpangolin (jonl) Thu 5 Jan 23 07:52
permalink #53 of 338: fruitbatpangolin (jonl) Thu 5 Jan 23 07:52
Via email from fruitbatpangolin: Greetings and salutations to the SOTW Psychopomps, Jon and Bruce, and wishing well to all Well Dwellers, Denziens and assorted Entities, this fine January morning of Uh-Oh-Fa-Fo-Ho-Ho-Ho2023 (Anno-Domino). That said, despite the wishing well, I'm not going to throw down any coins for luck. Partly from the risk of injury to those who dwell below, but mostly due to an egregious supply side issue regarding both luck and coin. Though, as chance would have it, I have afforded an ideal headstate in which to peruse this year's SOTW. Namely, one of mild hallucinations, nervous twitches and insomnia, after presenting a slight case of delirium tremens as a seasonal gift to myself, in celebration of Saturnalia. However given that it is not a serious bout of DTs, possessing of itself only a fairly limited effects budget, I also find myself rapidly approaching the blurred event horizon of sobriety. You lucky, lucky people. And hopefully, what or whoever it is that is doing an impression of society these days can help me pragmatically apply this passing satire of sober clarity into some useful tasks over the coming year. For instance, I bet the people shovelling that raw marijuana off those dump trucks into the gay bars worldwide could do with some logistical software, or something. Thanks Bruce for the pointer. And despite the potential for moral anarchy and satanic decay, both professionally and ethically it would still seem a much better sector to get involved with than whatever the fuck it is that the established tech behemoths think that they are currently up to. Besides, doing that globally is tricky, especially given the current situation in Ukraine. Is a whole world of opportunity out there, really. About time we lived in an interesting maze.
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State of the World 2023: Bruce Sterling and Jon Lebkowsky
permalink #54 of 338: Stewart Dickson (jonl) Thu 5 Jan 23 07:56
permalink #54 of 338: Stewart Dickson (jonl) Thu 5 Jan 23 07:56
Via email from Stewart Dickson, Consulting Engineer at the Long Now Foundation <https://longnow.org/>: Just an observation, because I'm observing the WELL for the first time, via this rare (I suppose), world-readable conversation. You're using the Long Now five-digit date format. But, of course! Because WELL stands for Stewart Brand's Whole Earth 'Lectronic Link, I had no idea the whole WELL was using 5-digit years. Cheers! -Stewart Dickson [Note to Stewart: that was Bruce using the five digits, not the case for the whole WELL...]
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State of the World 2023: Bruce Sterling and Jon Lebkowsky
permalink #55 of 338: Bruno Boutot (jonl) Thu 5 Jan 23 07:58
permalink #55 of 338: Bruno Boutot (jonl) Thu 5 Jan 23 07:58
Via email from Bruno Boutot: These past few weeks, huge scandals involving McKinsey have erupted in France, in Quebec, and now in Canada. The abusive reliance on McKinsey by governments doesn't look much different from other kinds of mercenaries, like private armies or guns for hire. What place do you think the McKinseys of this world are taking in the world order to come? <https://www.cbc.ca/amp/1.6703626>
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State of the World 2023: Bruce Sterling and Jon Lebkowsky
permalink #56 of 338: Michael Bravo (jonl) Thu 5 Jan 23 08:04
permalink #56 of 338: Michael Bravo (jonl) Thu 5 Jan 23 08:04
Via email from Michael Bravo: I'd like to forcefully if respectfully disagree with Bruce Sterling on Cyber War as stated in #31. As offered, it is a very naive look at whichever definition of "cyber war" you may like. For a counterexample it is quite simple to point at the ongoing war in Ukraine. Nearly every success of Ukrainian military is underpinned by some kind of cyberwar capability - disruptive, covert or overt recon, stupid enemy slip-ups (like posting pics of active units with geolocation intact to social), etc and so on. And the extent to which Russian digital assets have been penetrated since the start of the war even just by the volunteer collectives is staggering, and the fallout from that hasn't even begun appearing on the horizon. But it will. There is just too much "cyber" (or compute, if you like) embedded into today's society in more layers than any non-specialist person usually imagines. It's not enough to "just bomb power plants" (and that "just" is also a gross oversimplification if I ever saw one)
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State of the World 2023: Bruce Sterling and Jon Lebkowsky
permalink #57 of 338: Bruce Sterling (bruces) Thu 5 Jan 23 08:29
permalink #57 of 338: Bruce Sterling (bruces) Thu 5 Jan 23 08:29
It's good to hear from Patrick Lichty after the two weirdest years in the culture industry that I ever witnessed. How people made do in the art world in those circumstances -- no events, no galleries, no museums, no concerts, no seminars or schoolrooms even -- there's a picaresque survival yarn for each of a million people, and no two stories alike. I was in lockdowns in three different cities; it was edifying to see all the busy-ness of daily life just stopping, again and again, in place after place. That Twilight Zone atmosphere of deserted streets; I thought to myself that I would never forget it, but in fact I *will* forget it. It was so extraordinary that, in retrospect, I have a hard time fitting it into my head. And yet, I'm confident that this decade will have more of that -- not Covid quarantines, but other massive reactions to other massive emergencies, just as peculiar and probably just as semi-effective.
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State of the World 2023: Bruce Sterling and Jon Lebkowsky
permalink #58 of 338: Bruce Sterling (bruces) Thu 5 Jan 23 08:33
permalink #58 of 338: Bruce Sterling (bruces) Thu 5 Jan 23 08:33
Personally, I didn't come to any particular harm by the quarantines. I had good fortune, they weren't traumatic times for me. What were those times like? They were "like nothing else," but also they were remarkably like "nothing." They felt somewhat like a general strike or a hurricane evacuation, but they also had this novel sci-fi vacuity to the textture of the days. Huge, surreal absences. The lack of transport nose and any sky-contrails was a big aspect. The people were in hiding from one another, but also the big machines were absent and silent. Italian cityscapes were like Di Chirico paintings, solemn, silent and suggestively angular. I've never seen another situation where quotidian daily life was so comprehensively invalidated. It makes you understand why the indignant Chinese -- (there were a lot of young Chinese women in the recent anti-lockdown protests, it was a kind of primal, last-ditch "life-woman-freedom" upheaval, and they forced Xi to back down) -- they would actually prefer to have a million people die, than to semi-live that way. Human mortality is tragic, but not as disconcerting as massive, endless and eventually fruitless efforts to avert it.
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State of the World 2023: Bruce Sterling and Jon Lebkowsky
permalink #59 of 338: Bruce Sterling (bruces) Thu 5 Jan 23 08:34
permalink #59 of 338: Bruce Sterling (bruces) Thu 5 Jan 23 08:34
I caught Covid and I survived the disease, but I found myself in quite a different cultural sensibility after that. I'm calmer about catastrophes and emergencies, because I was in one, and it could have easily carried me off. Life has an odd sweetness now, like an extra dessert-plate. It won't surprise me all if I catch Covid again and it kills me, because I'm somewhat older and weaker, while it's considerably better-evolved. However, I don't fret much about it. I'm pretty confident that I'll see some other 2020s event more dramatic, presently; that the covid pandemic was a kind of subdued, bucolic prelude to that. Like a cat chasing a huge, indifferent flock of city-pigeons before they all burst into flight. As a futurist, I wonder what eventuality I'm missing. Not pandemics, Futurists tend to talk almost too much about pandemics, it's one of the commonest grand, hand-wavey "black swan" lessons -- "You see, we could suffer a big pandemic, just like AIDS or the Spanish Flu!" I was even working on a novel with a pandemic in it when the pandemic hit us. I put that book aside, since, though. Don't feel quite ready to deal with that. Have to re-think it some.
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State of the World 2023: Bruce Sterling and Jon Lebkowsky
permalink #60 of 338: Bruce Sterling (bruces) Thu 5 Jan 23 08:36
permalink #60 of 338: Bruce Sterling (bruces) Thu 5 Jan 23 08:36
Recently I completed a fantastic story that involved being in Belgrade during the pandemic. Trying to capture that dark-fantasy air of a bizarre yet becalmed situation with "no reality checks" because there's no objective reality left for anyone to measure anything against. When I finished this yarn, I realized that I didn't know who should read it, or what publisher or readership would want to mess with it. It's just not standard genre product. I do have a feeling that it's very of this cultural moment, but it's so sui generis that it feels like it just has to sit there, waiting for something. https://medium.com/@bruces/balkan-cosmology-by-bruce-sterling-2022-9a06b9b28bc 0
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State of the World 2023: Bruce Sterling and Jon Lebkowsky
permalink #61 of 338: The Year of the Rabid (jonl) Thu 5 Jan 23 08:49
permalink #61 of 338: The Year of the Rabid (jonl) Thu 5 Jan 23 08:49
I never would have predicted that a global pandemic would play out thew way it actually did, especially the politicization of public health. However well we think we can predict what's coming, we usually get it wrong.
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State of the World 2023: Bruce Sterling and Jon Lebkowsky
permalink #62 of 338: @mackreed@mastodon.social (factoid) Thu 5 Jan 23 10:58
permalink #62 of 338: @mackreed@mastodon.social (factoid) Thu 5 Jan 23 10:58
Greetings to Jon, Bruce, all WELLperns and the good souls joining the good fight to Figure It All Out in SOTW'23. It surprises me to see no reply yet to #3, which IMHO has the potential to reshape Society Itself even more profoundly than has the entire internet: "3) AI is becoming more visible and usable, and just as misunderstood as ever. A good example is ChatGPT, a conversational AI that bends over backwards to distinguish itself from human intelligence. Also popular: image generation AIs like Dall-E and Midjourney. Questions abound: will AI become dangerous, and if so, what is the nature of the danger? Will AI replace humans in the workplace? Will and AI driver your car? If so, when your car runs a pedestrian down, who's responsible? It just goes on and on." The Algorithm (thanks, Zuck, Sergey/Larry, Jeff) already glowers like a meth-crazed grizzly over the smoking ruin of a society that used to know better how to disagree with words rather than blows. Commercialized social media weaponized disagreement, sold it to bad actors and - in the end - murdered TRVTH and fomented actual insurrection because we began to *trust it* as our window on reality. Journalism is dead. Demagogues and influencers rule our understanding of What's Real. We used to argue at dinner. Now we claw each other bloody without seeking to understand the root of opposing viewpoints, and arm ourselves against The Others. Because if you're not with us, you need to die. Now: enter MidJourney, deepfakery, and every other flavor of algorithmic image engine. In the hands of bad actors (the same ones who used social media to yank on the levers of power as if it were a toddler's busybox) images manufactured by AI can have just as much power to disrupt and destroy perceptions of fact as did the mass-media from news/commentary to The Loudest Shouter Wins. Now consider what image AI means for the original work of visual artists; Did you know that BY DEFAULT, Adobe uses images create with its programs to train an AI they're developing? I learned so this morning, and raced to do this: - Log into your Adobe account (https://adobe.com) - Go to "View Account" (top-right) - Click "Account and Security/Privacy and Security" - Uncheck everything unless you think you need it. Will illustrators, photographers, and 3D modelers be earning a buck five, 10 years from now? Consider what happened to journalism when computers helped society decide that opinion trumps fact. To put a finer point on it, the Algorithm is only as trustworthy as the engineers who built it and trained it. See Facebook, Twitter, and the generation of vapid hotties that the Lensa.ai app began turning female users into last month when its bot-generated avatars started cluttering up Insta: https://arstechnica.com/information-technology/2022/12/lensa-ai-app-causes-a-s tir-with-sexy-magic-avatar-images-no-one-wanted/ Might it go otherwise? Synthesizers and the Roland 808 didn't destroy the careers of studio musicians - in fact, they birthed new musics, new genres, and new ideas that inspired practitioners of every art. OTOH, Rick Beato opines, auto-tune DESTROYED popular music: https://www.youtube.com/watch?v=6IV29YNTH3M&feature=emb_imp_woyt It's early days yet for image AI. Anything could happen. Just - as you decide how to trust its inevitable rise - remember how cute, fuzzy, and wonderful it felt in 2007 to share images and opinions with your distant kin on Facebook or your online chums on Twitter. And think about how you will let it change your life. Now: If you haven't already done so, try ChatGPT: https://chat.openai.com/chat Tell it to write a job application, a song, a short story, a news article in any style you like. Within seconds, it will cough up a reasonable simulacrum, perfectly spelled, punctuated, and with - quite often - more than a passing flair for a nice turn of phrase. As Beato points out in the above-linked video, Chat GPT does a shit job of aping Ed Sheehan lyrics. But what happens when the output is not so easily exposed? What happens when you disseminate AI-generated job-application letters, executive memos, Supreme Court "leaks", declarations of war? Doomsday scenarios are too easily imagined and - god, we can only hope - quickly defused. While software companies furiously gin up solutions for detecting bot-speak (https://www.google.com/search?q=anti-chatgpt), professors are fretting they might have to start insisting all papers be written by hand: https://www.google.com/search?q=professors+chat+gpt+hand-written The real threat is deeper and more systemic and organic, as our trust in the technology's ability to perform, dream, articulate, and communicate for us grows. Original thinking won't die as quickly as, say, semi-civil public discourse. But all too soon, it might start to resemble a vapid hottie.
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State of the World 2023: Bruce Sterling and Jon Lebkowsky
permalink #63 of 338: Nancy White (choco) Thu 5 Jan 23 11:04
permalink #63 of 338: Nancy White (choco) Thu 5 Jan 23 11:04
What will be amplified? What will be dampened? Who will be doing this?
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State of the World 2023: Bruce Sterling and Jon Lebkowsky
permalink #64 of 338: Shanta Stevens (jonl) Thu 5 Jan 23 11:28
permalink #64 of 338: Shanta Stevens (jonl) Thu 5 Jan 23 11:28
Via email from Shanta Stevens, broken into multiple posts because of its length. I posted this earlier and marked it 'hidden,' but found that the hidden post could not be read by anyone but members of the WELL. I am not a resident of the Well, so I am not certain that I understand the format, but I thought y'all might be amused by some of this SCRYTCH that I have been cobbling together... Specifically regarding this entry in the 2023 State of the World top ten list... 9) A new era of psychedelic therapies and the potential for legal recreational consciousness expansion. But is it really an expansion? Or do we just want to get high? https://people.well.com/conf/inkwell.vue/topics/522/State-of-the-World-2023-Br uc e-St-page01.html#post11 <CAVEAT>: Regarding any discussion I have with anyone about psychedelics ever... First of all, I would like to stress that I recognize that psychedelics are definitely NOT for everyone... I would seriously recommend consulting a healthcare professional before anyone considered any kind of experimentation! But fortunately, scientists have been discovering that there are therapeutic & neuroprotective benefits (for trauma/anxiety/depression), even from ***sub-psychedlic micro-dosages*** of psilocybin mushrooms (which have been decriminalized in a growing number of nations, states, counties & municipalities). https://doubleblindmag.com/stamets-stack/ And this improved neuroplasticity has been observed (even with microdosing) with other psychedelics (which certainly still require more research & further decriminalization efforts) https://www.frontiersin.org/articles/10.3389/fpsyt.2021.724606/full -- If there is one thing that I can impress upon people with whom I discuss these issues, I would like to highlight that we cannot stress enough how crucial *set & setting* are, as well as dosage... this is it: *Integration practices <before, during & after> are crucially important!* https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9386447/
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State of the World 2023: Bruce Sterling and Jon Lebkowsky
permalink #65 of 338: Shanta Stevens (jonl) Thu 5 Jan 23 11:29
permalink #65 of 338: Shanta Stevens (jonl) Thu 5 Jan 23 11:29
I personally believe that this is, in essence, the answer to the million dollar question before me: how do we follow up on our first Documentary, _DMT: The Spirit Molecule_ (which has been seen by no less than 40 million people, as a conservative estimate) https://www.youtube.com/watch?v=fwZqVqbkyLM Currently, we have already filmed approximately 25% of our interviews for the sequel (with Reggie Watts signed on as narrator... he was also our first interview out in LA, a year ago). While we are gearing up for our Kickstarter campaign (planned for this February), we have been putting the finishing touches on our website... https://www.uniphi.studio/ The working title has been _The Conscious Molecule_ ...because our director wants to cover the ideas of panpsychism that are coming back into vogue in traditional philosophy, as well as information theory & physics https://www.noemamag.com/the-conscious-universe/ We livestreamed the ESPD55 academic conference (many of whom have actually spent most or all of the last 55 years in the Amazon)... There were presentations on everythjing from social justice issues of reciprocity with the indigenous cultures who have safeguarded the medicine plants for thousands of years... particularly as we are shifting from a Psychedelic Renaissance into a Psychedelic Industrial Age? https://espd55.com/ At the same time as we were in Britain livestreaming ESPD55 for the academics, many of the psychedelic celebrities & influencer types were at the Davos World Economic Forum Medical Psychedelic panel, lobbying for funding for their nascent industries. https://docsend.com/view/wvhsxq2y9j5c8rpy As far as the pharmaceutical corporations go, they seem to be most interested in patenting permutations of psychedlics that have the desired effects of treating ptsd, depression, anxiety, etc. but without the "excess cogitation" (& requisite cost in hours of therapy time with a counselor). So, they are essentially still trying to sing the same tune that they have been since they colluded with the insurance corporations to make psychedelics illegal everywhere in 1971... which is that they just want everyone to buy their panacea pills, stop misbehaving and get back to work asap! https://www.nature.com/articles/s41586-020-3008-z
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State of the World 2023: Bruce Sterling and Jon Lebkowsky
permalink #66 of 338: Shanta Stevens (jonl) Thu 5 Jan 23 11:30
permalink #66 of 338: Shanta Stevens (jonl) Thu 5 Jan 23 11:30
Meanwhile, neuroimaging studies, like those conducted by Dr. David Nutt at Imperial College are showing profound results with traditional psychedelics: https://espd55.com/speakers/david-nutt/ There is now extensive evidence that serotonin 5-HT2A receptor acting psychedelic drugs such as psilocybin LSD and DMT work by producing a profound disruption of ongoing oscillatory activity in the brain. This disrupts the segregation of key brain networks and leads to increased crosstalk between them. in this state of increased disorder [entropy] abnormal thinking processes such as rumination that underpin disorders such as depression and addiction become temporally disrupted allowing the patient to "escape" from them. also the increased connectivity allows the person to discover new insights in their past and develop new thoughts about the future which can endure well after the trip is over. this prolonged benefit can be accentuated by psychotherapy and also by the serotonin receptor stimulation that in rodent models can be shown to increase dendrite growth and synaptogenesis. Our recent neuroimaging studies of depressed patients recovering after psilocybin treatment reveals that the increased connectivity seen during the trip persists for weeks afterwards and is associated with increased flexibility of brain function, an outcome not seen with traditional antidepressant treatments. We think this increased flexibility may explain the experiences of increased connectedness with the world that patients often report and the improved wellbeing scores they register. Another crucial recent discovery regarding endogenous DMT was covered in this 2019 documentary, _DMT Quest_ https://dmtquest.org/future-research/ https://youtu.be/My95s6ZryPg Which referenced this paper https://www.nature.com/articles/s41598-019-45812-w This is the idea that really stuck out to me: During cardiac arrest, people seem to experience a flood of hyperactivity in the brain... including high amounts of dmt: The main function of this process may actually be primarily neuroprotective, rather than psychedelic... although the visual/auditory/kinesthetic & emotional factors are particularly noticeable side effects... So, I am leaning back towards more of a focus on endogenous DMT production... Although I also recognize that since prehistoric times, humans all over the world have been augmenting these experiences with external sources, as well... *People need to understand that we can endogenously produce profound psychological states without consuming external sources of these molecules!*
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State of the World 2023: Bruce Sterling and Jon Lebkowsky
permalink #67 of 338: Shanta Stevens (jonl) Thu 5 Jan 23 11:31
permalink #67 of 338: Shanta Stevens (jonl) Thu 5 Jan 23 11:31
Meanwhile, another of our colleagues, Dr. Bruce Damer has finally publically revealed his techniques for hypnagogic visualization that have provided him *eureka* moments of genius throughout his life... which have only been magnified through his careful combination with Ayahuasca ritual (which in turn produced the research that became the August 2017 cover story in Scientific American). We are looking forward tointerviewing him more about his methods of endogenous DMT production to experience states of genius. "Long a tool for artists and musicians, could psychedelics refined with endogenous practices yield a high-octane fuel to advance science and engineering?" https://archive.org/details/22-05-25-espd-55-dr-bruce-damer-high-time-for-scie nc e <that's one of our livestreams from ESPD55> It still blows my mind that The Veteran's Administration was able to successfully fund one of the largest psychedlic research & therapy clinics in the world here in Austin, last year! And I certainly look forward to calling upon Charles B. Nemeroff, M.D., Ph.D. & Greg Fonzo, Ph.D. very soon! https://dellmed.utexas.edu/news/dell-med-launches-center-to-study-psychedelics -f or-treatment-of-depression-anxiety-ptsd They have already started their first trials! (and it sounds... pretty freakin' hardcore!) https://www.keranews.org/health-wellness/2022-10-13/can-psychedelics-combat-pr ol onged-grief-dell-medical-school-launches-study-to-find-out
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State of the World 2023: Bruce Sterling and Jon Lebkowsky
permalink #68 of 338: The Year of the Rabid (jonl) Thu 5 Jan 23 11:32
permalink #68 of 338: The Year of the Rabid (jonl) Thu 5 Jan 23 11:32
Oops, broken links: <https://dellmed.utexas.edu/news/dell-med-launches-center-to-study-psychedelics -for-treatment-of-depression-anxiety-ptsd> They have already started their first trials! (and it sounds... pretty freakin' hardcore!) <https://www.keranews.org/health-wellness/2022-10-13/can-psychedelics-combat-pr olonged-grief-dell-medical-school-launches-study-to-find-out>
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State of the World 2023: Bruce Sterling and Jon Lebkowsky
permalink #69 of 338: Shanta Stevens (jonl) Thu 5 Jan 23 11:32
permalink #69 of 338: Shanta Stevens (jonl) Thu 5 Jan 23 11:32
This article makes a curious point: "(In the Upper Amazon, Ayahuasca) is viewed as a tool for diagnosis and prescription. Shamans in the Upper Amazon do not drink ayahuasca to heal; they drink ayahuasca to get information --- as Cocama shaman don Juan Curico puts it, "to screen the disease and to search the treatment." Mestizo shaman don Manuel Cordova says the same thing: "Ayahuasca, it tells you how, but by itself it cures nothing." If a patient comes to an Upper Amazonian shaman to be healed of, say, cancer, the traditional purpose of drinking ayahuasca is not to heal the cancer, but rather to determine both the etiology and the treatment of the disease." https://singingtotheplants.com/2009/01/ayahuasca-and-cancer/ However, those shamans may not have been aware of certain other activities produced by Ayahuasca "In summary, it is hypothesized that the combined actions of [-]-carbolines and DMT present in ayahuasca may diminish tumor blood supply, activate apoptotic pathways, diminish cell proliferation, and change the energetic metabolic imbalance of cancer cells, which is known as the Warburg effect," Schenberg wrote. "Therefore, ayahuasca may act on cancer hallmarks such as angiogenesis, apoptosis, and cell metabolism." https://www.psypost.org/2014/01/psychedelic-drug-ayahuasca-could-help-in-battl e- against-cancer-researcher-says-22353 DMT is also neuroprotective & contributes to neurogenesis. Although humans generally have the capacity to generate new neuronal cells, it is not always possible, leading to an interest in drugs and substances that can aid this process. "The challenge is to activate our dormant capacity to form neurons and thus replace the neurons that die as a result of the disease. This study shows that DMT is capable of activating neural stem cells and forming new neurons", says Morales. https://www.labroots.com/trending/neuroscience/19133/psychedelic-dmt-improves- me mory-neurogenesis https://youtu.be/o98crZWauPI https://www.nature.com/articles/s41398-020-01011-0 "It has also been observed that sigma-1 receptor agonists are potentially neuroprotective (Frecska et al., 2013). DMT has been shown to reduce neuronal inflammation via the sigma-1 receptor (Szabo et al., 2014) and can also induce neuronal plasticity, a long-term recuperative process that goes beyond neuroprotection (Tsai et al., 2009; Ruscher et al., 2011; Kourrich et al., 2012). Sigma-1 receptors can also influence cell survival and proliferation (Collina et al., 2013) and Frecska et al. (2013) have suggested that DMT is protective during cardiac arrest and perinatal development." <https://www.frontiersin.org/articles/10.3389/fnins.2018.00536/full> <https://www.sciencedirect.com/science/article/abs/pii/S0014488620300765?via%3D ihub>
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State of the World 2023: Bruce Sterling and Jon Lebkowsky
permalink #70 of 338: Shanta Stevens (jonl) Thu 5 Jan 23 11:33
permalink #70 of 338: Shanta Stevens (jonl) Thu 5 Jan 23 11:33
Here's an off-the-cuff summary that a sometimes local medical colleague, Dr. Jens relayed to me in June, 2022 concerning his opinion about the function of DMT and its role in natural selection "a survival advantage emergency organ (or function produced by a system of organs) that allows for temporary dissolution of self in priority of instinct and clarity of perception " Regarding that quote, I suggested that the idea that DMT allows us to transcend the self & visualize our instincts (often anthropomorphically) during survival emergencies is a perspective that seems reminiscent of the Hermetic Mystery: "in times of danger or distress, in (W)hom do you place your trust?" https://realitysandwich.com/the-use-of-dmt-in-early-masonic-ritual/ https://podcasts.apple.com/us/podcast/p-d-newman-freemason-and-author-alchemic al ly-stoned/id1468028667?i=1000469422470 Not only Freemasonry, but also Christianity, Judaism, & Islam all reference the sacred nature of Acacia &/or Mimosa (and curiously, combining their root bark with Syrian Rue/Peganum Harmala plant produces the Mediterranean equivalent of Ayahuasca). They are also evergreens, so it makes sense that they would symbolize immortality. However, there has been an increasing degree of agreement that the ancients had extensive psychopharmacological knowledge. Acacia was sacred to Osiris, as well as Jehovah's burning bush, the ark of the covenant & the temple at Jerusalem (and also was used in medicine & as a ritual incense). https://catbull.com/alamut/Bibliothek/7616docid6743.pdf
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State of the World 2023: Bruce Sterling and Jon Lebkowsky
permalink #71 of 338: Shanta Stevens (jonl) Thu 5 Jan 23 11:33
permalink #71 of 338: Shanta Stevens (jonl) Thu 5 Jan 23 11:33
Also, there is considerable evidence that Syrian Rue/Peganum Harmala was the plant used to produce an entheogen known as Haoma in the roots of the Zoroastrian tradition (the same plant is still used in that tradition symbolically)... & the same plant may be also have been one of the principal ingredients used in the creation of the elixir known as Soma, mentioned in the Rig Veda (as mentioned above, it can also be used a potentiator of synergetic effects with Acacia/Mimosa, as well as with psychedelic mushrooms &/or cannabis) https://espd55.com/event/chemically-induced-otherworldly-experiences-of-zoroas tr ians-in-iran/ Will someone please tell Brian Muraresku that he should cover this in a sequel to _The Immortality Key_ ???!!!!! https://lareviewofbooks.org/article/the-psychedelic-sacrament-a-conversation-w ith-brian-c-muraresku/ If you are unfamiliar with Muraresku's work, he has discovered the smoking gun (archaeological evidence analyzed by mass spectrometer to prove that the Eleusinian tradition used Ergot-infused beverages) that explains the ancient mystery traditions & their connections to the formation of the original Xtian gatherings in ancient Greece https://youtu.be/iC6DDvzM6Nc
inkwell.vue.522
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State of the World 2023: Bruce Sterling and Jon Lebkowsky
permalink #72 of 338: Shanta Stevens (jonl) Thu 5 Jan 23 11:34
permalink #72 of 338: Shanta Stevens (jonl) Thu 5 Jan 23 11:34
So, going back to the generally beneficial aspects of integration techniques, as mentioned previously... In my experience, humans generally benefit from some kind of symbolic ritual to align themselves with their chosen ideals... Although many worthy traditions of mindfulness recommend non-attachment, and I think that there is certainly a time for that... I think that there are profound lessons to be learned from psychedelic states that take us back to the womb & perinatal imprinting (q.v. the work of Dr. Stanislav Grof), and just as babies that receive compassionate care generally grow up to be more well-adjusted adults... so, too will someone experiencing a psychedelic state benefit from exercises of kindness... but i suppose that could still be me projecting my preconceived notions & values onto other people... sigh... i will work on gathering more evidence... but in all my considerable life-experience, my research points to this as fact... although i guess i might temper my words here with a reference to my initiation in a Bwiti temple with Ibogaine... there is an aspect of toughlove... "breaking open the head" ...to allow our spirit to enter the graveyard & commune with the ancestors... their message is still for us to see ourselves through the eyes of those who love us unconditionally. https://ibogaine.mindvox.com/articles/ibogaine-story-staten-island-project/age nt-coincidence/ https://ibogaine.mindvox.com/articles/ibogaine-story-staten-island-project/bwi ti/
inkwell.vue.522
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State of the World 2023: Bruce Sterling and Jon Lebkowsky
permalink #73 of 338: Shanta Stevens (jonl) Thu 5 Jan 23 11:34
permalink #73 of 338: Shanta Stevens (jonl) Thu 5 Jan 23 11:34
...Moreover, what tied Bwiti specifically to Gnosticism (even ancient Gnosticism seen through the post-quantum eyes of Philip Dick) was that, as Fernandez points out: "For these Bwitists... religion was not a matter of faith... It was a very pragmatic technique for understanding, predicting and controlling--in short a science or pre-science of hidden to things. To believe in something despite lack of evidence or evidence to contrary, which is the Western religious condition, was foreign to their attitudes. Fang had alway had good evidence for their beliefs"--via ready access to plant sacrament, like the Gnostics. In VALIS, in a passaga on Gnostic sacraments, Beal found an Ibogaine parallel which was just uncanny: "48. ON OUR NATURE. It is proper to say: we appear to be memory coils (DNA carriers capable of experience) in a computer-like thinking system which, al-though we have correctly recorded thousands of years of experiential information, and each of us po ssesses somewhat different deposits from all the other life forms, there is a malfunction--a failure--of memory retrieval. There lies the trouble in our particular subcircuit. "Salvation" through gnosis--more properly anamnesis (the loss of amnesia )--although it has individual significance for each of us--a quantum leap in perception, identity, cognition, understanding, world- and self-experience, including immortality--it has greater and further importance for the system as whole, inasmuch as thes e memories are data needed by it and valuable to it, to its overall functioning. Therefore it is in the process of self-repair, which includes: rebuilding our subcircuit via linear and orthogonal time changes, as well as continual signalling to us to stimulate blocked memory banks within us to fire and hence retrieve what is there. The external information or gnosis, then, consists of disinhibiting instructions, with the core content actually intrinsic to us--that is, already there (first observed by Plato; viz: that learning is a form of remembering). The ancients possessed techniques (sacraments* and rituals) used largely in the Greco-Roman mystery religions, including early Christianity, to induce firing and retrieval, mainly with a sense of its restorative value to the individuals;the Gnostics, however, correctly saw the ontological value to what they called the Godhead itself, the total entity." <an excerpt from Tractates Cryptica Scriptura, pub. 1978 in VALIS, by PKD> The more Dana got into it, the more he realized having VALIS** in 1980 was like being handed a roadmap to understanding gnostic substances, Ibogaine and Bwiti, back in the very beginning. But the Ibogaine story is replete with these coincidences.
inkwell.vue.522
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State of the World 2023: Bruce Sterling and Jon Lebkowsky
permalink #74 of 338: Shanta Stevens (jonl) Thu 5 Jan 23 11:35
permalink #74 of 338: Shanta Stevens (jonl) Thu 5 Jan 23 11:35
"The long waking dream period that follows the absorption of iboga or ibogaine at a subtoxic dose (or oneirophrenic dose according to Naranjo) appears to be responsible for a temporary destructuring of the ego, followed by its restructuring. "This hypothesis is consistent with the observations made by the ethnologists in their studies of the Mitsogho Bwiti, and may be compared to the hypotheses of Michel Jouvet and Sir Francis Crick (C. Debru, 1990) on the role of dreams in the programing and deprograming of basic behavior patterns, resulting in a new individuation of the human brain. "Normally, the stages of wakefulness of the human brain are: waking, NREM (slow wave or deep) sleep, PGO (pontogeniculo-occipital) waves, and REM (rapid eye movement or paradoxical) sleep. REM sleep is the period of dreams. "Michel Jouvet and Sir Francis Crick consider PGO waves to be the principal coding tool that acts at the cortical level in recording the genetic and epigenetic acquisitions necessary for the individuation of the human brain. "In addition, through random activation mechanisms, the PGO waves eliminate from certain types of neuronal networks an informational overload linked to pathological behavior. This is what C. Debru calls "cleaning out the neuronal circuitry." "REM sleep apparently undertakes a sorting out process among the "residues" stirred up by the PGO wave sleep pattern and disposes of these residues during dreaming. "Michel Jouvet (letter of November 7, 1990) wrote: "The oneiric effects observed in humans and which are produced by hallucinogens do not enable us to approach the dream mechanism directly, because it does appear that these two phenomena cannot be link ed together as one. "We know, however, that the principal difference between dreams and hallucinations resides in the way in which the stages of wakefulness are organized, with the suppression of REM sleep and the intrusion of PGO waves in the arousal (waking) stage and i n NREM (or slow) sleep. "The new organization becomes: waking (arousal) stage, stage of PGO waves, hallucination stage, sleep stage, and it appears possible that hallucinatory manifestations, the waking dream, eliminate "residues" stirred up by the PGO wa ve pattern in the absence of REM sleep."--(Pharmacodynamics and Therapeutic Applications of Iboga and IbogaineRobert Goutarel, with Otto Gollnhofer and Roger Sillans, French National Scientific Research Center) "You were right," exulted Carlo. "Ibogaine is fundamentally different from the 'clear' psychedelics. And Howard is right in that there's no way to duplicate the Ibogaine effect without the visualizations! It is a waking dream--but REM-like, not tr ue REM." What it is exactly is explained in Goutarel's next lines: "Near Death Experiences "According to the Mitsogho, the initiate will see the Bwiti only twice in his life: on the day of his initiation and on the day of his death. "This means that the visions at the approach of death, what are called near death experiences (NDE), are the same as those termed normative visions. "We know that at the time of dying, some individuals see their whole life pass before them. In those who are "rescued from death," a spectacular transformation is observed. They no longer fear death, they feel stronger, more optimistic, calmer, and con template their life more positively." The brain is capable of generating another state, which the conscious mind recognizes as "dreamlike." Normally the waking mind has only indirect access to the activities of the acetylcholine pathways. Normally the activity of the sleeping brain only se eps into consciousness slowly--during the few minutes of REM we get every night. But a real emergency can trigger a survival reflex, the NDE, which gets both halves of the brain up and functioning stereoscopically, at the same time. The serotoninergic pathways, organized as the ego, get direct access to all the disorganized acti vity of the cholinergic pathways, which are perceived as "five or six television programs going at once." Ibogaine triggers the NDE reflex. The "splitting of the skull," which releases the visions, is the same as the jerk you sometimes feel just as you're falling asleep, greatly amplified because your serotonin and acetylcholine are pumping at the same ti me, and your DA is way down, which normally doesn't happen. But in the NDE, the conscious mind gets access to PGO wave material: direct genetic instructions from the non-nucleated genetic material in all of your cells. These are the genes that are passed on directly from your mother; they don't lose anything from generation to generation, unless a cosmic ray hits them. You get nothing from your father but nucleated genes passed on through the sperm, which is the ge netic equivalent of an earth satellite. The egg by comparison is a minature planet. Primitive cells that replicate by division, like amoebas, pass all their memory along through these non-nucleated genes. But about a billion years ago some cells invented sex, swapping of genetic instuctions contained in the nucleus via mitosis. Much more complex organisms became possible, but to maintain access to cellular memory, through the acetylcholine pathways, they had to sleep . All the activity of the sleeping mind is summarized several times a night in the REM phase, which when you remember your dreams, makes a "report" from the unconscious to the conscious mind. Sleep doesn't just raise cellular memories to consciousness, though; every night your mind makes a "back-up" of the day's memories all the way down in the non-nucleated genetic material of the cells. Since these little packets of information don't de grade much from generation to generation, you have ancestral memories going back a quarter of a million years. But always through the mother, which is why Fred, on Ibogaine, experienced the concentration camps through the eyes of his mother and not his fa ther. The thing is that these cellular memories might have in them the informa-tion you need to survive in a real emegency, when you have no chance to sleep until the answer just comes to you, in a dream. There's a lot of situations, a lot of scenarios in a quarter million years. So before there was language, before there was writing, we developed the NDE, this trick reflex that allows the conscious mind to access PGO wave activity directly. Ibogaine triggers the NDE reflex chemically, without having to be near death. Ibogaine turns the serotoninergic and cholinergic pathways into a super-augmented, "sterescopic" entity, capable of scanning ancestral memory in the nonnucleated genetic material of your cells: the ancestors... -- Akashic Record: HP Lovecraft, Psychedelia, Ancient Astronauts, and Occult Theories of Creativity https://2012diaries.blogspot.com/2014/02/akashic-record-hp-lovecraft-psychedel ia .html <this excerpt seems particularly pertinent, regarding the lovecraftian aspectd of the 23 enigma in this context> Narby's thesis in The Cosmic Serpent is worth dwelling upon for a moment. He concluded that when in trance, shamans "take their consciousness down to the molecular level and gain information related to DNA." The idea in essence, however, was not entirely new. Timothy Leary had come to more or less the same conclusion after experimenting with mushrooms and (copiously) with LSD. In a television interview from the Millbrook days, Leary spoke of gaining access to "the long telephone wire of history, which goes back two billion years, and which is buried somewhere inside your brain and mine....we are neurologically and biochemically in touch with thousands of generations that came before us, and the record of these previous evolutionary attempts are there, it's just that our mental/symbolic minds can't decode these messages." In the idea of an accessible database of genetic memory contained in our DNA, we find a new quasi-scientific metaphor for the major idea which has recurred throughout this essay, be it the Platonic Mind At Large of Huxley, the occult Akashic Record of the Theosophists, or the Indiana Jones-like lost temple of Cayce's Hall of Records. In his treatment of Leary's eight circuit model of consciousness in Prometheus Rising, Robert Anton Wilson calls this the Collective Neurogenic Circuit, which "processes DNA-RNA-brain feedback systems and is "collective" in the sense that contains and has access to the whole evolutionary "script", past and future." All of this speaks to a fascinating notion which is perhaps preeminent among the religious ideas of the modern west: that our minds contain something far older and smarter than ourselves, and with which we attain a fleeting communication in the shared register of myths, dreams, and the fantastic or weird. To attain communion with these deeper strata of consciousness is perhaps the shared heretical goal of Jungians, surrealists, psychedelic voyagers, and a certain type of fantastic or popular artist who embodies elements of all of the above, sometimes unconsciously. Philip K. Dick observed that the symbols of the Divine appear first in the trash stratum. William James conceded that many religious manifestations and visions could be accounted for by appealing to the individual's psyche and unconscious, but he left it open that the unconscious might itself be precisely designed to receive the influx of higher transmissions: "The notion of the subconscious self certainly ought not at this point of our inquiry be held to exclude of notion of a higher penetration. If there be higher powers able to impress us, they may get access to us only through the subliminal door". Whether such vast storehouses of ancestral and possibly futuristic knowledge actually exist or not, and whether it happened that a Providence misanthrope of dubious literary reputation was tapping into one due to nightly soakings of DMT from his overactive pineal gland, I leave as usual to the reader to decide. Interestingly, though, the idea of the Hall of Records within seems to have occurred to Lovecraft, as we find in the conclusion to the earlier quoted fragment The Descendent: "There rose within him the tantalizing faith that somewhere an easy gate existed, which if one found would admit him freely to those outer deeps whose echoes rattled so dimly at the back of his memory. It might be in the visible world, yet it might be only in his mind and soul. Perhaps he held within his own half-explored brain that cryptic link which would awaken him to elder and future lives in forgotten dimensions; which would bind him to the stars, and to the infinities and eternities beyond them."
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State of the World 2023: Bruce Sterling and Jon Lebkowsky
permalink #75 of 338: Shanta Stevens (jonl) Thu 5 Jan 23 11:35
permalink #75 of 338: Shanta Stevens (jonl) Thu 5 Jan 23 11:35
Speaking of extraterrestrial exploration, it seems crucial to talk about the looming competition over Lunar mining operations... https://www.fastcompany.com/90789419/china-moon-mineral-discovery-heres-why-ch an gesite-y-could-fuel-a-gold-rush-for-lunar-mining Especially in the wake of the recent net positive fusion experiement, there is definitely a conflict brewing https://www.spectator.co.uk/article/fusion-energy-and-the-coming-fight-for-the -m oon/ -- But let's be honest... human biological systems are not designed to function outside of our homeostatic gravity well... and even the most hardened cynics who have gone to space often still experience massive brain change through salutogenesis ("the overview effect") https://aethyrflux.livejournal.com/114684.html -- Along that theme... In 2021, Bruce Damer suggested a "new key theme for our times: boundary disillusion!" https://soundcloud.com/levityzone/075-levityzone-boundary-dissolution?in=levit yz one/sets/latest-levity-zone-podcast "The late Terence McKenna...called for boundary dissolution as an elixir for humanity on its rickety road to shooting the wormhole through to long-term survival and thrival. Terence's elixirs were psychedelics and i proposed that there are other potions that can dissolve these boundaries which divide us terence and i collaborated on avatar cyberspace explorations in the late 1990s. I picked his brain and picked up and ran with one of his other key questions: how does novelty arise i.e how do more complex things compress out of simpler ones? Cracking some of this code over the past two decades has led to our current proposal for how life itself emerged and a new perhaps more complete view of the dual nature of nature. We propose that nature rests on a base substrate of collaboration supporting a theater of competition above it is not strictly survival of the fittest driving evolution forward." For those of you who are not already familiar with Bruce Damer's work in Astrobiology & the Hot Springs Evolutionary Hypothesis, I am willing to bet that you will be fascinated! https://extendedevolutionarysynthesis.com/the-hot-spring-hypothesis-for-the-or ig in-of-life-and-the-extended-evolutionary-synthesis/ Meanwhile, back on Earth... we have many options of methods to produce transformative states of consciousness... Jamie Wheal, Steven Kotler & the Flow Genome Project published a great book that identified a trillion dollar underground economy... forcing us to rethink how we can all lead richer, more productive, more satisfying lives... Driven by four accelerating forces--- psychology, neurobiology, technology and pharmacology history.https://www.flowgenomeproject.com/stealing-fire Robin Arnott & Andromeda refer to their VR experiences as "technodelics" https://www.soundself.com/technodelic-manifesto https://www.enterandromeda.com/ss-science And I have been rather impressed by the research being done by Dr. Jeffrey Martin & colleagues at the Transformative Technology Lab.... particularly their studies around producing states of Fundamental Wellbeing and Persistent Non-Symbolic Experience (aka non-duality, persistent mystical states, unitive states, transcendental consciousness, enlightenment, illumination & emergent wisdom, etc.) https://transtechlab.org/our-research/ https://www.nonsymbolic.org/7-myths/thank-you/the-science https://www.nonsymbolic.org/SOC-2018-Presentation.pdf http://www.nonsymbolic.org/PNSE-Article.pdf However, as easily as I have seen that it can be for some people to glimpse Fundamental Wellbeing (in 14 weeks or less, in most cases), this kind of profound life-changing experience has still been somewhat elusive to others. In the post-modern world that we inhabit with all of its demands towards materialism & accelerationism, many dismiss such pursuits as incompatible with their current worldviews. I have also been concerned for some time that even though modern rational humans refuse to believe in the spirit world, that they may in fact still be extensively subject to others' beliefs (and the Leviathan structures which have been set in motion by others' beliefs), in profound ways that they do not consciously realize. At some times, I may have been inclined to ask, whether or not "individuals" even exist in the way that we are led to believe that we do? That last question may need to wait, so let us assume that individuals do exist, but perhaps it is just that we are still subject to external forces which we may or may not be aware of...
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