Case Study Report: 8

Opening Statement: The client, has been in the study for 42 weeks and has remained sober.

Patient Background Information The client is a 52-year old, white women who has been married 32 years, is a high school graduate, and is unemployed. She has a history of alcoholic gastritis, alcoholic hepatitis, alcoholic pancreatitis, myocardial infarction, and depression. Concomitant medications include pancrelipase (Creon), multivitamin,,Maalox, docusate (Colace), nizatidine (Axid), and sertraline (zoloft). zoloft was discontinued 4/15/94, and fluoxetine (Prozac) was started. The client's mother died of a CVA and alcoholism at age 63. The client has two daughters, ages 21 and 29; the 21-year-old reportedly drinks heavily and is estranged from the client. The client's spouse also reportedly is a "heavy drinker." The client began drinking at age 17 and reports drinking heavily for the past 10 years, with an average of 38 drinks per week. The client reported that her alcoholism has caused her many physical problems, and basically has lost track of her life.

No previous CD treatment.

Naltrexone Treatment and Results: Client began on a 50mg dose per day and has remained on this dose for 42-weeks. The client feels that naltrexone eliminated cravings and has remained abstinent since 2/18/94. The client has been treated for depression with Zoloft, which was discontinued 4/15/94; she has been taking Prozac from 4/16/94 to present. The client reports attending two AA support groups per week. The client currently is participating in Amendment 2 and is scheduled to complete this phrase in April 1995. As previously stated, the client feels the naltrexone eliminated cravings for alcohol. Prior to Amendment 2, the client expressed a great fear of remaining abstinent through the Christmas holidays without naltrexone. The client was very grateful to continue the naltrexone study while working on building a sober lifestyle.

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